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. 2021 Jun;27(6):e204608. doi: 10.3201/eid2706.204608

Table. Widely accepted nomenclature for HRSV genes and proteins and gene annotation of strains HRSV A2 and HRSV B1*.

Gene or genome region
Proteins
Open reading frame genome position, nt
Annotation† Genome position, nt†
Strain A2‡ Strain B1¶ Annotation Abbreviation Strain A2 Strain B1
Leader region
1–44
1–44






NS1 45–576 45–577 Nonstructural protein 1 NS1 99–518 99–518
NS2
596–1098
594–1098

Nonstructural protein 2
NS2

628–1002
626–1000
N 1126–2328 1125–2327 Nucleoprotein N 1141–2316 1140–2315
P 2330–3243 2331–3244 Phosphoprotein P 2347–3072 2348–3073
M 3253–4210 3254–4208 Matrix protein M 3262–4032 3263–4033
SH 4220–4629 4218–4630 Small hydrophobic protein SH 4304–4498 4303–4500
G 4674–5596 4675–5600 Attachment glycoprotein G 4689–5585 4690–5589
F
5649–7551
5653–7552

Fusion glycoprotein
F

5662–7386
7666–7390
M2
7598–8558
7609–8568

Matrix protein 2
Matrix protein M2–1 M2–1 7607–8191 7618–8205
Matrix protein M2–2
M2–2

8160–8432
8171–8443
L
8491–15068
8501–15080

Polymerase protein
L

8499–14996
8509–15009
Trailer region 15069–15223 15081–15225

*HRSV, human respiratory syncytial virus.
†Nucleotide annotations for leader and trailer region, and for indicated HRSV genes from the first nucleotide of the gene start signal [GGGGCAAAT(A/G); GGAGCAAAAT in case of the L gene] through the last adenosine residue of the gene end signal [AGT(T/A)A(T/A/G)(A/T)(A/T)(A/T)An].
‡HRSV/A/USA/A2/2015 (45); GenBank accession number KT992094.
¶HRSV/B/USA/B1/1985/B1 (46); GenBank accession number AF013254.1.