Table 1. Invasive pneumococcal disease cases and deaths averted by pneumococcal conjugate vaccines, United States, 1997–2019*.
| Year | No. observed, by age, y |
No. expected, by age, y |
No. averted |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <1 | 1 | 2–4 | Overall | <1 | 1 | 2–4 | Overall | Annual | Cumulative | |||
| No. cases | ||||||||||||
| 1997 | 5,360 | 6,712 | 3,635 | 15,707 | 5,360 | 6,712 | 3,635 | 15,707 | NA | NA | ||
| 1998 | 6,220 | 7,630 | 4,286 | 18,136 | 6,220 | 7,630 | 4,286 | 18,136 | NA | NA | ||
| 1999 | 6,176 | 7,772 | 3,837 | 17,785 | 6,176 | 7,772 | 3,837 | 17,785 | NA | NA | ||
| 2000 | 5,699 | 6,139 | 3,469 | 15,306 | 6,053 | 7,428 | 3,883 | 17,364 | 2,057 | 2,057 | ||
| 2001 | 2,099 | 2,645 | 3,143 | 7,887 | 6,299 | 7,539 | 3,852 | 17,689 | 9,802 | 11,860 | ||
| 2002 | 1,521 | 1,261 | 1,813 | 4,596 | 6,202 | 7,830 | 3,866 | 17,899 | 13,304 | 25,164 | ||
| 2003 | 1,642 | 1,405 | 1,530 | 4,577 | 6,241 | 7,696 | 3,936 | 17,874 | 13,296 | 38,460 | ||
| 2004 | 1,485 | 1,253 | 1,454 | 4,192 | 6,301 | 7,730 | 3,983 | 18,013 | 13,821 | 52,281 | ||
| 2005 | 1,450 | 1,419 | 1,467 | 4,336 | 6,286 | 7,796 | 4,019 | 18,101 | 13,765 | 66,046 | ||
| 2006 | 1,366 | 1,458 | 1,395 | 4,219 | 6,344 | 7,767 | 4,019 | 18,130 | 13,911 | 79,956 | ||
| 2007 | 1,680 | 1,296 | 1,560 | 4,537 | 6,511 | 7,826 | 4,036 | 18,372 | 13,835 | 93,792 | ||
| 2008 | 1,517 | 1,284 | 1,420 | 4,221 | 6,487 | 8,018 | 4,057 | 18,562 | 14,341 | 108,133 | ||
| 2009 | 1,485 | 1,309 | 1,654 | 4,449 | 6,284 | 7,975 | 4,099 | 18,358 | 13,910 | 122,043 | ||
| 2010 | 1,352 | 1,051 | 1,611 | 4,014 | 6,204 | 7,726 | 4,144 | 18,074 | 14,060 | 136,103 | ||
| 2011 | 832 | 670 | 1,012 | 2,515 | 6,221 | 7,755 | 4,109 | 18,085 | 15,571 | 151,674 | ||
| 2012 | 616 | 541 | 712 | 1,870 | 6,163 | 7,777 | 4,068 | 18,009 | 16,139 | 167,813 | ||
| 2013 | 578 | 595 | 814 | 1,988 | 6,171 | 7,709 | 4,036 | 17,916 | 15,928 | 183,741 | ||
| 2014 | 629 | 407 | 754 | 1,790 | 6,208 | 7,721 | 4,033 | 17,963 | 16,173 | 199,914 | ||
| 2015 | 733 | 513 | 610 | 1,856 | 6,253 | 7,769 | 4,031 | 18,053 | 16,198 | 216,112 | ||
| 2016 | 526 | 212 | 167 | 906 | 6,208 | 7,828 | 4,032 | 18,068 | 17,163 | 233,275 | ||
| 2017 | 452 | 314 | 625 | 1,391 | 6,112 | 7,770 | 4,052 | 17,934 | 16,544 | 249,818 | ||
| 2018 | 446 | 309 | 627 | 1,382 | 6,040 | 7,651 | 4,061 | 17,752 | 16,370 | 266,188 | ||
| 2019 |
446 |
309 |
627 |
1,382 |
|
6,040 |
7,651 |
4,061 |
17,752 |
|
16,370 |
282,558 |
| No. deaths | ||||||||||||
| 1997 | 151 | 34 | 17 | 202 | 151 | 34 | 17 | 202 | NA | NA | ||
| 1998 | 78 | 47 | NA | 126 | 78 | 47 | NA | 126 | NA | NA | ||
| 1999 | 29 | 45 | 60 | 134 | 29 | 45 | 60 | 134 | NA | NA | ||
| 2000 | 130 | 113 | 57 | 301 | 138 | 137 | 64 | 340 | 39 | 39 | ||
| 2001 | 22 | 46 | 57 | 125 | 103 | 66 | 36 | 204 | 79 | 118 | ||
| 2002 | 31 | NA | 32 | 62 | 101 | 68 | 36 | 205 | 143 | 261 | ||
| 2003 | 42 | 21 | 21 | 85 | 102 | 67 | 37 | 206 | 121 | 382 | ||
| 2004 | 39 | 48 | 20 | 107 | 103 | 67 | 37 | 207 | 101 | 483 | ||
| 2005 | 38 | 9 | 38 | 85 | 103 | 68 | 37 | 208 | 123 | 605 | ||
| 2006 | 29 | 9 | 47 | 85 | 104 | 68 | 37 | 209 | 124 | 729 | ||
| 2007 | 37 | 9 | 9 | 56 | 106 | 68 | 37 | 212 | 156 | 885 | ||
| 2008 | 37 | NA | 18 | 55 | 106 | 70 | 38 | 214 | 158 | 1,043 | ||
| 2009 | 36 | 9 | 9 | 54 | 103 | 70 | 38 | 210 | 156 | 1,199 | ||
| 2010 | 10 | 9 | 9 | 28 | 101 | 67 | 38 | 207 | 179 | 1,378 | ||
| 2011 | 38 | 19 | 28 | 85 | 102 | 68 | 38 | 207 | 123 | 1,501 | ||
| 2012 | 9 | 9 | NA | 19 | 101 | 68 | 38 | 206 | 187 | 1,688 | ||
| 2013 | 9 | 9 | 38 | 57 | 101 | 67 | 37 | 205 | 149 | 1,837 | ||
| 2014 | 19 | NA | 9 | 28 | 101 | 67 | 37 | 206 | 178 | 2,014 | ||
| 2015 | 10 | 9 | 19 | 38 | 102 | 68 | 37 | 207 | 170 | 2,184 | ||
| 2016 | 18 | 4 | 12 | 35 | 101 | 68 | 37 | 207 | 172 | 2,356 | ||
| 2017 | 28 | 19 | 38 | 85 | 100 | 68 | 38 | 205 | 120 | 2,476 | ||
| 2018 | 16 | 7 | 28 | 51 | 99 | 67 | 38 | 203 | 152 | 2,628 | ||
| 2019 | 16 | 7 | 28 | 51 | 99 | 67 | 38 | 203 | 152 | 2,780 | ||
*Values are rounded to the nearest whole numbers. NA, not applicable.