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. 2021 Jun;27(6):1737–1740. doi: 10.3201/eid2706.210558

Table. Characteristics of healthcare workers with severe acute respiratory syndrome coronavirus 2 reinfections, Brazil, 2020*.

Characteristic Healthcare worker
1 2 3 4
Underlying conditions
None
Chronic bronchitis
None
None
Hospitalized
No
No
No
No
Symptoms
First infection Fever, headache, chills, sneezing, coryza, and myalgia Headache, cough, myalgia, odynophagy, coryza, diarrhea, and ageusia Nasal congestion, coryza, cough, ageusia Fever, headache, myalgia, coryza, dry cough, vomiting, and malaise
Second infection
Headache, nasal congestion, odynophagia, ageusia, and anosmia
Cough, myalgia, odynophagia, anosmia, and diarrhea
Odynophagia, sneezing, coryza, diarrhea, ageusia, and anosmia
Odynophagia, dry cough, myalgia, malaise, coryza, and headache
Cycle threshold values
First infection† E gene: 35.24; N gene: 40.12 E gene: 31.8 E gene: 35.15 E gene: 34.80; RdRp gene: 39.86
Second infection‡
E gene: 31.14; N gene: 31.3; RdRp gene: 32.58
E gene: 20.45; N gene: 20.52; RdRp gene: 22.65
E gene: 26.04; N gene: 26.88; RdRp gene: 28.40
E gene: 23.72; N gene: 23.48; RdRp gene: 25.67
Time between symptom onsets, d 55 170 131 148

*E gene, envelope gene; N gene, nucleoprotein gene; RdRp gene, RNA dependent RNA polymerase gene.
†Real-time quantitative reverse transcription PCR selective for the envelope gene (2).
‡Nucleic acid amplification test using the GeneFinder COVID-19 Plus RealAmp Kit (OSANG Healthcare Co. Ltd., http://www.osanghc.com) (3).