Table 1. Variations in the Different Organ Weights (g) in Different Treatments^a.

			weight of the organs (g)
			subacute toxicity
		acute toxicity	male					female					teratogenicity
organs	control	2000 mg/kg	control	5 mg/kg	10 mg/kg	20 mg/kg	40 mg/kg	control	5 mg/kg	10 mg/kg	20 mg/kg	40 mg/kg	control	40 mg/kg
brain	1.5 ± 0.2	1.56 ± 0.2	1.3 ± 0.3	1.3 ± 0.1	1.4 ± 0.2	1.3 ± 0.6	1.2 ± 0.6	1.5 ± 0.4	1.6 ± 0.6	1.5 ± 0.2	1.5 ± 0.3	1.4 ± 0.1	1.4 ± 0.2	1.5 ± 0.12
heart	0.3 ± 0.1	0.44 ± 0.1	0.5 ± 0.2	0.6 ± 0.2	0.5 ± 0.3	0.5 ± 0.8	0.6 ± 0.5	0.6 ± 0.3	0.5 ± 0.3	0.6 ± 0.1	0.6 ± 0.2	0.65 ± 0.3	0.62 ± 0.3	0.6 ± 0.32
spleen	0.2 ± 0.1	0.3 ± 0.8	0.3 ± 0.4	0.5 ± 0.3	0.4 ± 0.4	0.3 ± 03	0.4 ± 0.3	0.4 ± 0.1	0.5 ± 0.3	0.4 ± 0.2	0.4 ± 0.3	0.3 ± 0.5	0.54 ± 0.1	0.53 ± 0.40
kidney	1.2 ± 0.1	1.5 ± 0.1	1.2 ± 0.3	1.2 ± 0.2	1.5 ± 0.8	1.4 ± 0.5	1.4 ± 0.1	1.1 ± 0.5	1.4 ± 0.2	1.2 ± 0.1	1.1 ± 0.5	1.3 ± 0.3	1.2 ± 0.1	1.23 ± 0.13
lungs	0.7 ± 0.3	0.92 ± 0.3	0.8 ± 0.5	0.8 ± 1.3	0.8 ± 0.6	0.7 ± 0.7	0.8 ± 0.6	0.9 ± 0.2	0.7 ± 0.1	0.7 ± 0.2	0.8 ± 0.3	0.8 ± 0.8	0.75 ± 0.2	0.76 ± 0.52
liver	6.9 ± 0.4	6.4 ± 0.5	5.8 ± 0.5	6.9 ± 0.1	6.3 ± 1.2	6.4 ± 0.3	6.6 ± 0.2	6.1 ± 0.4	6.6 ± 0.3	6.2 ± 0.3	6.9 ± 0.6	6.7 ± 0.5	6.24 ± 1.2	6.7 ± 1.3
stomach	0.9 ± 0.8	1.1 ± 1.2	1.1 ± 0.5	1.2 ± 0.0	1.6 ± 0.9	1.6 ± 0.8	1.9 ± 0.3	1.2 ± 0.3	1.2 ± 0.5	1.1 ± 0.5	1.5 ± 0.7	1.6 ± 0.8	1.2 ± 0.2	0.90 ± 0.62
ovaries	0.2 ± 1.5	0.1 ± 0.9						0.1 ± 0.1	0.1 ± 1.2	0.1 ± 0.1	0.1 ± 0.1	0.2 ± 0.9	0.32 ± 0.4	0.23 ± 0.3
testis	2.2 ± 1.2	2.6 ± 1.4	2.6 ± 0.4	2.2 ± 0.3	2.2 ± 0.5	2.1 ± 0.7	2.1 ± 0.1

^aData are presented as mean ± SEM; n = 5 for acute oral toxicity and n = 10 for teratogenicity and subacute toxicity studies.