Table 3. Sperm Count and Morphology of SF3-Treated Animals (Male) at Different Dose Levels in the Subacute Toxicity Studya.
| treatment group | sperm count (×106 sperm/mL) | normal sperm | hock less | bent | coiled/folded | detached head |
|---|---|---|---|---|---|---|
| control | 157 ± 3.4 | 74 ± 1.2 | 9 ± 2.1 | 55 ± 3.2 | 8.6 ± 2.3 | 10 ± 0.6 |
| SF3 5 mg/kg | 338 ± 2.1*** | 274 ± 2.2*** | 8 ± 0.9 | 25 ± 2.6 | 22 ± 2.1 | 9 ± 0.9 |
| SF3 10 mg/kg | 340 ± 5.1*** | 222 ± 3.4*** | 5 ± 0.12 | 21 ± 2.8 | 73 ± 1.5 | 19 ± 1.3 |
| SF3 20 mg/kg | 208 ± 4.6*** | 118 ± 4.6* | 14 ± 2.1 | 12 ± 3.6 | 26 ± 1.9 | 28 ± 1.5 |
| SF3 40 mg/kg | 215 ± 6.2*** | 149 ± 3.2** | 4 ± 1.3 | 18 ± 4.1 | 39 ± 2.3 | 5 ± 2.6 |
a
The data are represented as mean ± SEM with n = 5, *P < 0.05, **P < 0.01, and ***P < 0.001 were given in comparison with the control.