Table 3. Distance (Å) of 3-Phenylcoumarin Positions 2 and 7 to Selected CYP1 Residues with Standard Deviations.

	position 7 to heme iron			position 2 carbonyl to S122 (CYP1A1) or T124 (CYP1A2) hydroxyl oxygen or A133 methyl carbon (CYP1B1)
compound	CYP1A1	CYP1A2	CYP1B1	CYP1A1	CYP1A2	CYP1B1
13	4.5 ± 0.4	5.0 ± 0.6	4.9 ± 0.8	3.2 ± 0.8	5.4 ± 0.8	6.0 ± 1.2
14	4.1 ± 0.3	5.1 ± 0.3	4.6 ± 0.5	8.0 ± 0.5	9.8 ± 0.4	9.1 ± 0.8
15	5.5 ± 0.9	4.3 ± 0.5	5.2 ± 0.4	6.9 ± 1.1	5.3 ± 0.7	4.1 ± 0.5
16	4.5 ± 0.7	5.4 ± 0.4	4.5 ± 0.4	4.9 ± 1.5	6.3 ± 0.5	5.2 ± 1.0
17	4.7 ± 0.6	5.3 ± 0.5	5.1 ± 0.4	5.2 ± 1.1	6.3 ± 0.6	6.6 ± 0.5
18	4.1 ± 0.6	4.1 ± 0.5	4.4 ± 0.5	2.8 ± 0.3	6.5 ± 0.6	3.6 ± 0.3
19	5.0 ± 0.5	4.7 ± 0.3	6.8 ± 0.7	5.8 ± 0.8	5.1 ± 0.5	8.0 ± 0.8
20	3.9 ± 0.4	4.6 ± 0.5	4.4 ± 0.4	3.2 ± 0.7	5.1 ± 1.0	5.4 ± 0.5
21	4.4 ± 0.5	4.7 ± 0.5	4.8 ± 0.5	5.9 ± 0.7	5.8 ± 0.7	6.0 ± 0.7
22	4.3 ± 0.5	6.1 ± 1.2	4.4 ± 0.4	3.5 ± 0.8	6.7 ± 1.4	3.4 ± 0.3
23	4.5 ± 0.5	4.0 ± 0.4	4.7 ± 0.5	2.8 ± 0.4	5.0 ± 0.6	4.8 ± 0.6
average	4.5	4.8	4.9	4.8	6.1	5.6