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BIRB796 inhibits the proliferation of GBM cells in vitro. (A) Molecular structure of BIRB796. (B,C) Cell viability was measured with a CCK-8 assay after treatment of BRIB796 at various concentrations (0, 2, 4, 8, 16, 32, and 64 μM). (D–G) EdU assay showed that BIRB796 inhibited DNA synthesis in U87 and U251 cells in three independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001.
