Table 9. Results for analyses on data aggregated across studies: tests on frontal asymmetry on selected channel pairs.
Each row represents a given contrast × reference × control for confounds combination. N: number of participants included in given contrast, control for confounds: whether the FAA data was residualized with respect to confounding variables (age, gender and education); ES: effect size, measured as Cohen’s d for DvsHC and SvsHC contrasts and Spearman’s r for Dreg and allReg contrasts; CI: bootstrap confidence interval for the effect size; BF01: Bayes Factor for the null hypothesis.
| No. | Contrast | Space | N | Control for confounds | Aggregated channel pair analyses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pair 1 (F3–F4) | Pair 2 (F7–F8) | |||||||||||
| ES | CI | BF01 | ES | CI | BF01 | |||||||
| 1 | DvsHC | avg | 102 vs 144 | − | 0.147 | [−0.111, 0.396] | 3.831 | 0.098 | [−0.161, 0.338] | 5.405 | ||
| 2 | DvsHC | avg | 102 vs 143 | + | −0.011 | [−0.264, 0.244] | 7.042 | −0.006 | [−0.266, 0.240] | 7.042 | ||
| 3 | DvsHC | csd | 102 vs 144 | − | 0.188 | [−0.069, 0.449] | 2.597 | −0.100 | [−0.354, 0.164] | 5.319 | ||
| 4 | DvsHC | csd | 102 vs 143 | + | 0.103 | [−0.159, 0.362] | 5.236 | −0.164 | [−0.417, 0.108] | 3.300 | ||
| 5 | SvsHC | avg | 77 vs 121 | − | 0.065 | [−0.236, 0.359] | 5.780 | −0.025 | [−0.320, 0.240] | 6.250 | ||
| 6 | SvsHC | avg | 77 vs 120 | + | 0.024 | [−0.269, 0.315] | 6.211 | −0.144 | [−0.447, 0.140] | 4.016 | ||
| 7 | SvsHC | csd | 77 vs 121 | − | 0.053 | [−0.223, 0.355] | 5.952 | −0.108 | [−0.372, 0.179] | 4.878 | ||
| 8 | SvsHC | csd | 77 vs 120 | + | 0.053 | [−0.222, 0.350] | 5.952 | −0.110 | [−0.389, 0.179] | 4.831 | ||
| 9 | DReg | avg | 102 | − | 0.188 | [0.006, 0.354] | 1.387 | 0.007 | [−0.186, 0.188] | 8.065 | ||
| 10 | DReg | avg | 102 | + | 0.175 | [−0.018, 0.348] | 1.742 | −0.029 | [−0.211, 0.155] | 7.752 | ||
| 11 | DReg | csd | 102 | − | 0.099 | [−0.072, 0.260] | 4.975 | 0.065 | [−0.136, 0.252] | 6.579 | ||
| 12 | DReg | csd | 102 | + | 0.051 | [−0.131, 0.216] | 7.092 | 0.048 | [−0.157, 0.255] | 7.194 | ||
| 13 | allReg | avg | 315 | − | 0.085 | [−0.017, 0.184] | 4.651 | 0.029 | [−0.080, 0.126] | 12.5 | ||
| 14 | allReg | avg | 314 | + | 0.041 | [−0.063, 0.143] | 10.87 | 0.001 | [−0.120, 0.104] | 14.085 | ||
| 15 | allReg | csd | 315 | − | 0.059 | [−0.054, 0.166] | 8.333 | −0.026 | [−0.141, 0.082] | 12.821 | ||
| 16 | allReg | csd | 314 | + | 0.055 | [−0.056, 0.168] | 8.772 | −0.048 | [−0.158, 0.059] | 9.901 | ||
DvsHC – diagnosed and healthy controls; SvsHC – sub-clinical and healthy controls; allReg – linear regression for all subjects together; DReg – linear regression for only diagnosed subjects; avg – average reference; csd – current source density.