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. 2021 Mar 23;61(4):1570–1582. doi: 10.1021/acs.jcim.0c01285

Table 2. Example of Deorphanization Prediction from DISAE Ensemble Models.

orphan receptor (uniprot ID) Pfam drug drug target
A0A0C4DFX5 PF13853 Isoetharine ADRB1, ADRB2
A0A126GVR8 PF13853 Ganirelix GNRHR
A0A1B0GTK7 PF00001 Levallorphan OPRM1
A0A1B0GVZ0 PF00001 Xamoterol ADRB1, ADRB2
A0A286YFH6 PF13853 Degarelix GNRHR
A3KFT3 PF13853 Degarelix GNRHR
C9J1J7 PF00001 Levallorphan OPRM1
C9JQD8 PF00001 Lixisenatide GLP1R
E9PH76 PF00001 Ganirelix GNRHR
E9PPJ8 PF13853 Xamoterol ADRB1, ADRB2