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. 2021 Mar 11;121(8):4561–4677. doi: 10.1021/acs.chemrev.0c00752

Figure 15.

Figure 15

(A) Influence of COL1 and OPN gradient on Runx2 expression after 7 day under (a, c) osteogenic medium (OSM) and (b, d) DMEM. (e) Quantitative results of Runx2 on the COL1 and OPN gradients. Reprinted with permission from ref (291). Copyright 2019 Wiley-VCH. (B) Adipogenesis/osteogenesis on OD–AA gradient under mixed medium after 14 days. (a) Nile red staining and (b) Calcein Blue staining, respectively. (c) Quantification results along the gradient. Reprinted with permission from ref (231). Copyright 2015 Elsevier, Ltd.