linear double gradient |
composition: the gradients range
from 25–100% PLLA |
(254) |
roughness: starting from the PDLLA-rich end, surface roughness
increased as the fraction of PLLA increased; roughness then reached
a plateau between 60 and 80% PLLA before becoming somewhat smoother
from 80–100% PLLA |
wettability: 30–94° |
(145) |
stiffness: 85 MPa to ∼7 MPa |
orthogonal gradient |
pore size: ranging from hundreds to tens of nanometers |
(255) |
peptide density: not shown |
dual topography gradient: on one axis varied from 8–100
μm space between the 8 μm grooves and on the other axis
from ∼5 nm to ∼1 μm in depth |
(256) |
topography: the groove width ranging from 5–95 μm
with a constant ridge depth of 3.4 μm |
(257) |
chemistry: varying from a hydrocarbon to a nitrogen-containing
polymer |
topography: parallel grooves with
widths varying from 5–95
μm, separated by 5 μm wide ridges |
(253) |
wettability: WCA ranging from 55–96° |
roughness: Ra value ranging from 0.8–4.1
μm |
(31) |
nanoparticle density:
particle number decreased linearly from
around 74 particles per μm2 to 0 |
constant groove width of 8 μm and
with ridge width increasing
from 8 μm in 0.5 μm steps across 10 mm |
(33) |
gradient of groove depth spanning more than 2 orders
of magnitude
(less than 10 nm to over 1000 nm) |
peptide concentration gradient: GRGDS concentrations
ranging
from ∼15–90 pmol/cm2 and BMP-2 concentration
range from ∼0–25 pmol/cm2
|
(258) |
stiffness: 6–89 MPa |
(146) |
WCA: 29–90° |
stiffness: 0.5–1.3 kPa |
(259) |
Fn: a roughly 5-fold difference between
the highest and lowest
densities |