Table 2.

Univariate and multivariate Cox regression analysis of overall survival in 218 esophageal cancer cases.

	Univariate analysis		Multivariate analysis
Variables	HR (95% CI)	P value	HR (95% CI)	P value
Age (years), < 65 vs ≥ 65	1.279 (0.939–1.744)	.119
Sex, male vs female	0.707 (0.479–1.043)	.081
Pathologic type, ulcerative vs others	1.238 (0.888–1.726)	.208
Histologic grade, 1 + 2 vs 3	1.058 (0.753–1.487)	.746
Clinical response, resistance vs sensitivity	1.331 (0.956–1.851)	.090
Tumor size (cm), > 4 vs ≤ 4	1.244 (0.902–1.716)	.092
pT categories, T3 + T4 vs T1 + T2	1.977 (1.244–3.142)	.004	1.563 (0.939–2.602)	.086
LNM, positive vs negative	2.349 (1.528–3.611)	<.001	1.868 (1.118–3.122)	.017
TNM stage, III + IV vs I + II	2.050 (1.479–2.840)	<.001	1.243 (0.823–1.878)	.300
GNL3L expression, low vs high	1.504 (1.102–-2.053)	.010	1.483 (1.066–2.063)	.019