. 2021 Apr 2;7(5):1260–1274. doi: 10.1021/acsinfecdis.1c00025

Table 1. Structures and EC₅₀ Values of Representative DHB Compounds in the T. muris Adult Motility Assay^a.

All compounds investigated in this study are described in the Supporting Information File S2. No activity means no clear reduction in motility when tested at 100 μM. Where an EC₅₀ estimate is shown, it was calculated using a log-logistic model using the R package drc;⁴⁵ clogP values were calculated using ChemDraw Professional (16.0.0.82 (68)).

Table 1. Structures and EC50 Values of Representative DHB Compounds in the T. muris Adult Motility Assaya.

Table 1. Structures and EC₅₀ Values of Representative DHB Compounds in the T. muris Adult Motility Assay^a.