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. 2021 Apr 2;7(5):1260–1274. doi: 10.1021/acsinfecdis.1c00025

Table 2. EC50 Values for Compounds Active in the S. mansoni Schistosomula Roboworm Assaya.

  EC50 in S. mansoni schistosomula Roboworm assay (μM)
compound phenotype motility
9 OX03144 28.4 28.0
25 OX03146 25.5 25.6
15 OX03596 29.1 26.8
34 OX03599 14.2 18.3
17 OX03601 24.4 20.6
36 OX03698 28.5 26.6
6 OX03707 32.7 29.3
22 OX03824 40.9 36.8
35 OX03828 25.7 20.7
a

Compounds were screened at 10, 20, 30, 40, and 50 μM, and EC50 values were calculated for each of the screening parameters, phenotype, and motility.