Table 3. Concentration of Antiretrovirals Used for Microbial Susceptibility Assay^a.

drug name	max drug dose in one occasion (mg)	concentration in gutb (μg/mL)	Cmaxc (μg/mL)	50× Cmaxd
Efavirenz	600	240	4.07	203.5
Nevirapine	200	80	5.74	287
Rilpivirine	150	60	0.204	10.2
Abacavir	600	240	4.26	213
Emtricitabine	200	80	1.8	90
Lamivudine	300	120	2	100
Stavudine	40	16	0.536	26.8
Zidovudine	250	100	2.29	114.5
Tenofovir disoproxil fumarate	300	120	0.326	16.3
Tenofovir	245	98	0.05	2.5
Tenofovir Alafenamide	25	10	0.154	7.7
Atazanavir	400	160	3.152	157.6
Darunavir	800	320	6.5	325
Lopinavir	800	320	9.6	480
Ritonavir	100	40	0.85	42.5

^awww.hivdrugnteractions.org.

^bGut concentration (mg/L) was assessed on the basis of the formulations published by the European Medicines Agency.⁵⁴

^cC_max: maximum drug concentration in plasma.

^d50× C_max: estimation of concentration for drugs.