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Phylogenetic, epidemiological, and pathogenetic characteristics of SARS-CoV-2, MERS-CoV, and SARS-CoV
| Characteristics | SARS-CoV-2 | MERS-CoV | SARS-CoV |
|---|---|---|---|
| Phylogeny | Clade 1, cluster 2a | Clade 2 | Clade 1, cluster 2b |
| Reproductive number (R0) | 2–2.5 | 0.7 | 1.7–1.9 |
| Primary host | Bats | Bats | Bats |
| Intermediate host | Unknown (pangolins) | Camels | Palm civets |
| Receptor | Angiotensin converting enzyme 2 (ACE2) | Aminopeptidase-N; Dipeptidyl peptidase 4 (DPP4) | Angiotensin converting enzyme 2 (ACE2) |
