Figure 2.
Optimization of TCA1 based on analysis of the cocrystal structure. (a) Noncovalent interactions of TCA1 with DprE1 and modification regions. (b) Design and optimization of thiophene-arylamide compounds as DprE1 inhibitors.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.