Scheme 1. Synthesis of Benzoic Acid with Different Amide Substituents 4a–p.
Reagents and conditions: (a) Et3N, CH2Cl2, room temperature (rt), 3 h; (b) 1 mol/L LiOH aqueous solution, CH3OH, rt, 3 h.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.