Fig. 8.

Decomposition of free energy of binding in the spectinomycin binding pocket. The total ΔG of binding for each nucleotide interacting with spectinomycin 1 (dark red), 5 (dark orange), 9 (dark blue), 2 (light red), 6 (light orange), and 10 (light blue) in the binding pocket. The ΔG is an average over the 20 ns MD ensemble and the error bars represent the standard deviation