Figure 1: Trans-disease Meta-analysis.
a) Vertical Manhattan plots of the meta-analysis association results for psoriasis and T2D, showing genome-wide significant (pā¤5x10ā8) markers in red and shared loci identified by our trans-disease meta-analysis in blue. b) Regional association plots for the chromosome 10 locus in psoriasis and T2D (with the lead marker in purple). The locus is suggestive significant for each disease and genome-wide significant in the trans-disease meta-analysis.