TABLE 1:
Summary of clinical findings in cohort of patients with hybrid schwannoma-perineurioma.
| Case | Age | Sex | Site | Size (cm) | Depth | Initial diagnosis | Other neoplasms |
|---|---|---|---|---|---|---|---|
| Index | 61 | F | Thigh | 4.1 | SC | Hybrid schwannoma-perineurioma | |
| 2 | 11 | F | Ear | 1.0 | SC | Peripheral nerve sheath tumor NOS | |
| 3 | 38 | M | Mandible | 4.5 | SM | Hybrid schwannoma-perineurioma | BPOP |
| 4 | 33 | F | Lower leg | 1.0 | SC | Low-grade MPNST | |
| 5 | 52 | F | Thigh | 2.0 | SC | Spindle cell neoplasm of UMP | |
| 6 | 30 | F | Leg, NOS | 1.5 | D/SC | N/A | |
| 7 | 32 | M | Forearm | 2.2 | D/SC | SFT vs DFSP | |
| 8 | 34 | F | Scalp | 1.5 | SC | Desmoplastic melanoma | Remote femur OS |
| 9 | 57 | F | Bladder | 2.7 | Visceral | NF with atypical histologic features | |
| 10 | 13 | F | Flank | 1.0 | SC | Spindle cell tumor, R/O NTRK | |
| 11 | 53 | F | Thigh | 5.0 | IM | Hybrid schwannoma-perineurioma | Remote rectal Ca |
| 12 | 34 | F | Thigh | 2.7 | SC | Atypical spindle cell neoplasm | |
| 13 | 31 | M | Temple | 2.8 | D/SC | NF with atypical histologic features | |
| 14 | 30 | F | Neck | 1.3 | D | NF | Lung Ca (EML4-ALK) |
| 15 | 52 | M | Forearm | 1.9 | SC | Hybrid schwannoma-perineurioma | Schwannoma |
| 16 | 39 | F | Ear | 0.7 | SC | Hybrid schwannoma-perineurioma | |
| 17 | 21 | F | Abdominal wall | 1.6 | D | N/A | |
| 18 | 34 | M | Back | 3.5 | SC | NF |
Abbreviations: BPOP: bizarre parosteal osteochondromatous proliferation; Ca: adenocarcinoma; cm: centimeters; D: dermis; DFSP: dermatofibrosarcoma protuberans; IM: intramuscular; MPNST: malignant peripheral nerve sheath tumor; N/A: not applicable; NF neurofibroma; NOS: not otherwise specified; OS: high-grade osteosarcoma; R/O: rule-out; SC: subcutis; SFT: solitary fibrous tumor; SM: submucosa; UMP: uncertain malignant potential.