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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: J Mol Cell Cardiol. 2021 Mar 3;155:66–77. doi: 10.1016/j.yjmcc.2021.02.014

Fig. 7. Combinatorial screen using positive and negative regulators of sorafenib-induced apoptosis to identify pairwise combinations that may most effectively mitigate apoptosis.

Fig. 7.

Knockdown of positive regulator ROS coupled with overexpression of negative regulators FLT3, FGFR, PDGFR, VEGFR, or KIT results in the largest decrease in sorafenib-induced apoptosis.