Gene expression of Hmgcr (A), Cpt1a (B), and Srebp1 (C) in male and female mice was determined by qPCR as described in Material and Methods. Data are presented as mean ± SEM (n = 4-5). Statistical significance was determined by one-way ANOVA followed by Fisher's LSD as the post-hoc test. ‘p’ indicates difference between PFOS concentrations, ‘g’ indicates difference between gender, ‘d’ indicates difference between diets, ‘b’ indicated difference between genotypes. A letter indicates a p < 0.05, letter w/ * indicates p < 0.01, letter w/ ** indicates p < 0.001 and a letter w/ *** indicates p < 0.0001.