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. 2021 Mar 3;25(7):727–750. doi: 10.1007/s10157-021-02027-6

Table 14.

Intraday and interday correlation and variance of urinary creatinine of the same sample according to the mean urinary creatinine level

Mean of 2 urinary creatinine Regression line r p Bias of uCr
Range (mg/dl) n (mg/dl) (mg/dl)
Intraday
 3–4 h
  LC1-2  < 50.0 30 35.8 (29.1–43.6) 2uCr = 1.001 × 1uCr-0.06834 0.99  < 0.0001 − 0.1− 0.2 to 0.1)
Mcl-2 50.0 to < 90.0 30 64.7(58.4-76.5)a2 2uCr = 0.9962 × 1uCr-0.2676 0.99 < 0.0001 − 0.1− 0.4 to 0.4)
HC1-2  ≥ 90.0 28 128.1 (113.9–157.2)a2b2 2uCr = 1.013 × 1uCr-1.091 0.99  < 0.0001 0.5 (− 0.6 to 1.3)
 3 min
  LC3-4  < 50.0 30 35.9 (28.7–43.7) 4uCr = 1.008 × 3uCr + 0.07271 0.99  < 0.0001 0.1 (− 0.1 to 0.4)
  MC3-4 50.0 to < 90.0 29 64.4 (58.6–76.6)a2 4uCr = 0.9911 × 3uCr + 0.6046 0.99  < 0.0001 − 0.1(− 0.3 to 0.3)
  HC3-4  ≥ 90.0 29 126.9 (114.5–156.0)a2b2 4uCr = 0.9940 × 3uCr + 1.619 0.99  < 0.0001 0.5 (− 0.4 to 0.9)
Interday
 3–4 days
  LC1-3  < 50.0 30 35.3 (28.7–43.8) 3uCr = 0.9880 × 1uCr + 0.04098 0.99  < 0.0001 − 0.1 (− 0.2 to 0.1)
  MC1-3 50.0 to < 90.0 29 64.5 (58.5–76.7)a2 3uCr = 1.023 × 1uCr-1.095 0.99  < 0.0001 0.3 (− 0.1− 0.6)a1
  HC1-3  ≥ 90.0 29 127.6 (113.6–154.1)a2b2 3uCr = 1.030 × 1uCr-3.276 0.99  < 0.0001 1.1 (− 0.5 to 2.3)
  LC1-4  < 50.0 30 36.0 (29.0–43.8) 4uCr = 1.004 × 1uCr-0.1729 0.99  < 0.0001 0 (− 0.2 to 0.4)
  MC1-4 50.0 to < 90.0 30 64.8 (58.6–76.7)a2 4uCr = 1.014 × 1uCr-0.4915 0.99  < 0.0001 0.3 (− 0.2 to 1.0)
  HC1-4  ≥ 90.0 28 128.0 (114.2–157.6)a2b2 4uCr = 1.023 × 1uCr-1.646 0.99  < 0.0001 1.1 (− 0.1 to 2.4)
 3–4 days
  LC2-3  < 50.0 30 35.3 (28.8–43.6) 3uCr = 0.9859 × 2uCr + 0.1434 0.99  < 0.0001 0 (− 0.4 to 0.3)
  MC2-3 50.0 to < 90.0 29 64.6 (58.3–76.4)a2 3uCr = 1.022 × 2uCr − 1.109 0.99  < 0.0001 0.5(0–0.7)a2
  HC2-3  ≥ 90.0 29 127.7 (114.0–154.6)a2b2 3uCr = 1.016 × 2uCr − 2.048 0.99  < 0.0001 0.6 (− 0.5 to 1.4)
  LC2-4  < 50.0 30 35.9 (29.1–43.5) 4uCr = 1.002 × 2uCr − 0.09247 0.99  < 0.0001 0.1 (− 0.1 to 0.3)
  MC2-4 50.0 to < 90.0 30 64.9 (58.5–76.5)a2 4uCr = 1.017 × 2uCr − 0.7118 0.99  < 0.0001 0.5 (0.2–0.8)a2
  HC2-4  ≥ 90.0 28 127.8 (115.0–158.3)a2b2 4uCr = 1.010 × 2uCr − 0.5403 0.99  < 0.0001 0.8 (− 0.3 to 1.7)

The numbers of 1, 2, 3, and 4 represent the first, second, third, and fourth measurements, respectively, of urinary creatinine. Data are presented as median (IQR)

uCr urinary creatinine, LC low level of urinary creatinine; MC medium level of urinary creatinine; HC high level of urinary creatinine

a1p < 0.05 vs. LP

a2p < 0.01 vs. LP

b1p < 0.05 vs. MP

b2p < 0.01 vs. MP by the Steel–Dwass test; bias, difference of the later measurement against the previous measurement