Table 16.

Cut-off value (YI) of the urinary protein and uPCR to discriminate the samples of uACR ≥ 30 mg/gCr

Test variables	1uP	2uP	3uP	4uP	1uPCR	2uPCR	3uPCR	4uPCR
uACR ≥ 30 mg/gCr	52	47	47	45	52	47	47	45
ROC curve area	0.767	0.800	0.821	0.860	0.888a2	0.895a1	0.920a2	0.948a1
Standard error	0.051	0.047	0.045	0.040	0.034	0.036	0.029	0.022
p value	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001
CO(YI)a	4.0	3.3	3.4	3.6	0.08	0.08	0.07	0.08
Sensitivity	0.85	0.85	0.89	0.91	0.81	0.83	0.85	0.89
Specificity	0.64	0.68	0.68	0.72	0.81	0.85	0.85	0.88

The numbers of 1, 2, 3, and 4 represent the first, second, third, and fourth measurements, respectively, of urinary protein, albumin, and creatinine

CO(YI) cut-off value using Youden's index, uP urinary protein; uACR urinary albumin-to-creatinine ratio; uPCR urinary protein-to-creatinine ratio

^a1p < 0.01 vs. urinary protein

^a2p < 0.001 vs. urinary protein measured at the same time

^aUnit of uP, mg/dl; Unit of uPCR, g/gCr