Table 5. Comparisons of The Diagnostic Accuracy of 2D SWE Value, Age, Total Bilirubin, AST, GGT, APRi and Other Non-Invasive Fibrosis Markers in Predicting Histological Fibrosis Stages.

	AUROCs for ≥ F2	P	AUROCs for ≥ F3	P	AUROCs for F4	P
	n = 216		n = 216		n = 216
2D SWE (kPa)	0.868 (0.815, 0.910)		0.941 (0.901, 0.968)		0.884 (0.799, 0.917)
GGT (U/L)	0.645 (0.577, 0.709)	< 0.001	0.701 (0.636, 0.762)	< 0.001	0.603 (0.534, 0.669)	< 0.001
Age (days)	0.658 (0.590, 0.721)	< 0.001	0.659 (0.592, 0.723)	< 0.001	0.738 (0.673, 0.795)	0.005
AST (U/L)	0.637 (0.569, 0.702)	< 0.001	0.546 (0.476, 0.614)	< 0.001	0.602 (0.533, 0.668)	< 0.001
Total bilirubin (g/L)	0.629 (0.561, 0.694)	< 0.001	0.633 (0.565, 0.698)	< 0.001	0.507 (0.438, 0.575)	< 0.001
APRi	0.624 (0.555, 0.689)	< 0.001	0.540 (0.460, 0.598)	< 0.001	0.569 (0.500, 0.636)	< 0.001
	n = 163		n = 163		n = 163
2D SWE (kPa)	0.840 (0.774, 0.893)		0.937 (0.888, 0.969)		0.881 (0.822, 0.927)
Fibronectin (mg/L)	0.576 (0.496, 0.653)	< 0.001	0.670 (0.592, 0.741)	< 0.001	0.673 (0.596, 0.745)	0.005
Hyaluronic acid (ng/mL)	0.593 (0.513, 0.669)	< 0.001	0.655 (0.577, 0.728)	< 0.001	0.655 (0.577, 0.728)	0.002
Type IV collagen (ng/mL)	0.625 (0.546, 0.700)	< 0.001	0.614 (0.535, 0.689)	< 0.001	0.607 (0.528, 0.683)	< 0.001

All the p was compared with 2D SWE. APRi = aspartate aminotransferase to platelet ratio index, AST = aspartate aminotransferase, AUROCs = area under receiver operating characteristic curves, GGT = γ-glutamyltransferase, SWE = shear wave elastography, 2D = two-dimensional