Table 1. Baseline Demographics and Clinical Characteristics of the Validation Cohort.
Variables* | Value |
---|---|
Mean age (year) (± SD) | 67.5 (± 12.1), range 35–95 |
Sex, n (%) | |
Male | 54 (63.5) |
Female | 31 (36.5) |
CRC location | |
Colon | 63 (74.1) |
Rectum | 22 (25.9) |
CEA (ng/dL), median (IQR) | |
CRLM group | 31.8 (8.4–123.5) |
Non-CRLM group | 3.0 (1.9–8.3) |
T stage (tumor invasion depth), n (%) | |
T1–2 (confined to the bowel wall) | 12 (14.1) |
T3–4 (beyond the bowel wall) | 73 (85.9) |
N stage (nodal involvement), n (%) | |
N- (node negative) | 25 (29.4) |
N+ (node positive) | 60 (70.6) |
M stage, n (%) | |
M0 | 44 (51.8) |
M1 | 41 (48.2) |
Liver only | 25 (61.0) |
Lung only | |
Liver plus extrahepatic | 15 (36.6) |
Size of CRLM (cm), mean | 2.2 (± 2.2), range 0.4–12.4 |
Number of CRLM per patient, mean (± SD) | 2.5 (± 2.0), range 1–8 |
Number of CRLM ≤ 1 cm, n (%)* | 27 (27.3) |
Confirmatory method for CRML, n (%)* | |
Histopathology after hepatic resection or percutaneous biopsy | 63 (63.6) |
Suspicious MRI finding and follow-up imaging study | 36 (36.4) |
Values represent the number of subjects (%), median (IQR), or mean (± SD). *The total number of CRLMs was 99. CEA = serum carcinoembryonic antigen, CRC = colorectal cancer, CRLM = colorectal cancer liver metastasis, IQR = interquartile range, MRI = magnetic resonance imaging, SD = standard deviation