Table 3. Lesion-Based Diagnostic Performance of DLLD and Readers in the Binary Classification of Colorectal Liver Metastasis.

Testee	Sensitivity (%) (95% CI)	DLLD vs. Reader (P)	FPP (95% CI)	DLLD vs. Reader (P)
DLLD	81.82 [81/99] (72.68, 88.39)		1.330 [113/85] (1.052, 1.681)
Radiologist		0.795		< 0.001*
Reader-averaged	80.81 (73.03, 86.75)		0.357 (0.275, 0.464)
Reader 1	77.78 [77/99]		0.118 [10/85]
Reader 2	82.83 [82/99]		0.518 [44/85]
Reader 3	81.82 [81/99]		0.435 [37/85]
Resident		0.569		< 0.001*
Reader-averaged	79.46 (70.76, 86.08)		0.667 (0.531, 0.838)
Reader 4	82.83 [82/99]		1.306 [111/85]
Reader 5	80.81 [80/99]		0.471 [40/85]
Reader 6	74.75 [74/99]		0.224 [19/85]

^*Statistically significant. CI = confidence interval, DLLD = deep learning-based lesion detection algorithm, FPP = false positives per patient