Table 5. Per-Patient Diagnostic Performance of DLLD and Readers in the Binary Classification of Colorectal Liver Metastasis.

Testee	Sensitivity (%) (95% CI)	DLLD vs. Reader (P)	Specificity (%) (95% CI)	DLLD vs. Reader (P)
DLLD	87.50 [35/40] (73.30, 94.70)		22.22 [10/45] (12.40, 36.60)
Radiologist		0.790		< 0.001*
Reader-averaged	85.80 (78.40, 91.00)		66.67 (58.31, 74.10)
Reader 1	82.50 [33/40]		91.11 [41/45]
Reader 2	90.00 [36/40]		53.33 [24/45]
Reader 3	85.00 [34/40]		55.56 [25/45]
Resident		0.700		< 0.001*
Reader-averaged	85.00 (77.40, 90.30)		55.56 (47.09, 63.70)
Reader 4	90.00 [36/40]		24.44 [11/45]
Reader 5	87.50 [35/40]		57.78 [26/45]
Reader 6	77.50 [31/40]		84.44 [38/45]

^*Statistically significant. CI = confidence interval, DLLD = deep learning-based lesion detection algorithm