Table 2.
Univariate analysis and multivariate predictors for 90-day functional independence (mRS ≤ 2)
| Variable | mRS ≤ 2 (n=100) |
mRS > 2 (n=101) |
p-value | p-value (Wald’s test) | OR (95% CI) |
|---|---|---|---|---|---|
| Age-years, mean (SD) | 62.5 (12.8) | 69.5 (12.3) | 0.0001 | < 0.0001 | 0.94 (0.91–0.97) |
| Gender, n (%) | |||||
|
Male Female |
74 (54.0) 26 (40.6) |
63 (46.0) 38 (59.4) |
0.077 | 0.020 | 2.46 (1.15–5.26) |
| Baseline NIHSS, median (IQR) | 15.0 (10.0–18.0) | 18.0 (15.0–22.0) | < 0.00001 | 0.008 | 0.93 (0.88–0.98) |
| IV-FL, n (%) | |||||
|
Yes No |
64 (48.5) 36 (52.2) |
68 (51.5) 33 (47.8) |
0.656 | ||
| Baseline ASPECTS, median (IQR) | 9.0 (8.0–10.0) | 8.0 (7.0–9.0) | 0.0002 | < 0.0001 | 1.65 (1.33–2.06) |
| Intracranial Lesion site, n (%) | |||||
|
ICA ICA T-type M1 M2 or distal Hemodynamic TLs |
5 (38.5) 13 (32.5) 45 (51.1) 22 (62.9) 15 (60.0) |
8 (61.5) 27 (67.5) 43 (48.9) 13 (37.1) 10 (40.0) |
0.062 | ||
| Extracranial Lesion | |||||
| 1. Etiology, n (%) | |||||
| Plaque | 69 (45.1) | 84 (54.9) | 0.021 | ||
| Dissection | 31 (64.6) | 17 (35.4) | |||
| 2. Type, n (%) | |||||
| Occlusion | 59 (50.4) | 58 (49.6) | 0.886 | ||
| Subocclusion or Stenosis | 41 (48.8) | 43 (51.2) | |||
| Collateral Flow, n (%) | |||||
| Good | 56 (62.9) | 33 (37.1) | < 0.00001 | 0.013 | 0.57 (0.37–0.87) |
| Moderate | 34 (50.7) | 33 (49.3) | |||
| Poor | 10 (22.2) | 35 (77.8) | |||
| Anesthesia, n (%) | |||||
|
General Anesthesia Conscious Sedation |
42 (41.2) 58 (58.6) |
60 (58.8) 41 (41.4) |
0.017 | ||
| Intracranial Thrombectomy, n (%) | |||||
| TA | 52 (51.5) | 49 (48.5) | 0.141 | ||
| SCoT | 23 (38.3) | 37 (61.7) | |||
| eCAS, n (%) | |||||
|
Yes No |
63 (54.3) 37 (43.5) |
53 (45.7) 48 (56.5) |
0.154 | ||
| Antiplatelet Therapy | |||||
| 1. All, n (%) | |||||
|
Yes No |
61 (53.5) 39 (44.8) |
53 (46.5) 48 (55.2) |
0.256 | ||
| 2. Class, n (%) | |||||
|
ASA P2Y12 Inhibitors GpIIb/IIIa Inhibitors |
27 (48.2) 3 (100) 31 (56.4) |
29 (51.8) 0 (0) 24 (43.6) |
0.237 | ||
| Order of treatment, n (%) | |||||
|
Anterograde approach Retrograde approach |
32 (54.2) 31 (54.4) |
27 (45.8) 26 (45.6) |
1 | ||
| Timing-minutes, mean (SD) | |||||
|
OTG GTR |
250.1 (121.0) 70.3 (43.3) |
257.9 (117.9) 84.7 (42.8) |
0.652 0.022 |
||
| Complications, n (%) | |||||
|
No Yes |
90 (52.9) 10 (32.3) |
80 (47.1) 21 (67.7) |
0.049 | 0.009 | 0.27 (0.10–0.72) |
| mTICI, n (%) | |||||
|
2b-3 0-2a |
88 (56.4) 12 (26.7) |
68 (43.6) 33 (73.3) |
0.0006 | ||
| Extracranial ICA Recanalization, n (%) | |||||
|
Yes No |
93 (53.5) 7 (25.9) |
81 (46.5) 20 (74.1) |
0.012 | 0.001 | 6.05 (2.03– 18.06) |
| SICH, n (%) | |||||
|
Yes No |
0 (0) 100 (55.9) |
22 (100) 79 (44.1) |
< 0.00001 |