Table 3.
Univariate analysis for technical outcomes (mTICI 2b-3 and Extracranial ICA Recanalization)
| Variable | mTICI 0-2a (n=52) |
mTICI 2b-3 (n=175) |
p-value |
|---|---|---|---|
| Age-years, mean (SD) | 65.5 (11.3) | 66.1 (13.4) | 0.748 |
| Gender, n (%) | |||
|
Male Female |
36 (23.4) 16 (21.9) |
118 (76.2) 57 (78.1) |
0.867 |
| Baseline NIHSS, median (IQR) | 16.0 (12.0–20.8) | 16.0 (11.0–20.0) | 0.719 |
| IV-FL, n (%) | |||
|
Yes No |
32 (21.9) 20 (24.7) |
114 (78.1) 61 (75.3) |
0.625 |
| Baseline ASPECTS, median (IQR) | 8.5 (7.8–9.0) | 9.0 (8.0–10.0) | 0.114 |
| Intracranial Lesion site, n (%) | |||
|
ICA ICA T-type M1 M2 or distal Hemodynamic TLs |
4 (26.7) 12 (28.6) 16 (16.5) 12 (29.3) 8 (25.0) |
11 (73.3) 30 (71.4) 81 (83.5) 29 (70.7) 24 (75.0) |
0.332 |
| Extracranial Lesion | |||
| 1. Etiology, n (%) | |||
|
Plaque Dissection |
37 (21.5) 15 (27.3) |
135 (78.5) 40 (72.7) |
0.718 |
| 2. Type, n (%) | |||
|
Occlusion Subocclusion or Stenosis |
35 (26.9) 17 (17.5) |
95 (73.1) 80 (82.5) |
0.111 |
| Collateral Flow, n (%) | |||
| Good | 21 (21.2) | 78 (78.8) | 0.361 |
| Moderate | 15 (20.0) | 60 (80.0) | |
| Poor | 16 (30.2) | 37 (69.8) | |
| Anesthesia, n (%) | |||
|
General Anesthesia Conscious Sedation |
26 (25.0) 26 (21.1) |
78 (75.0) 97 (78.9) |
0.528 |
| Intracranial Thrombectomy, n (%) | |||
| TA | 21 (19.4) | 87 (80.6) | 0.574 |
| SCoT | 16 (23.2) | 53 (76.8) | |
| eCAS, n (%) | |||
|
Yes No |
18 (13.6) 34 (35.8) |
114 (86.4) 61 (64.2) |
0.0001 |
| Order of treatment, n (%) | |||
|
Anterograde approach Retrograde approach |
8 (11.9) 10 (15.4) |
59 (88.1) 55 (84.6) |
0.619 |
| Timing-minutes, mean (SD) | |||
|
OTG GTR |
261.5 (105.0) 87.0 (42.3) |
251.3 (122.1) 73.3 (43.2) |
0.572 0.064 |
| Complications, n (%) | |||
|
Yes No |
14 (36.8) 38 (20.1) |
24 (63.2) 151 (79.9) |
0.034 |
| Extracranial ICA Recanalization, n (%) | |||
|
Yes No |
30 (15.2) 22 (73.3) |
167 (84.8) 8 (26.7) |
< 0.00001 |
| Variable | No Extracranial ICA Recanalization (n=30) |
Extracranial ICA Recanalization (n=197) |
p-value |
|---|---|---|---|
| Age-years, mean (SD) | 65.8 (13.4) | 65.8 (12.8) | 0.998 |
| Gender, n (%) | |||
|
Male Female |
20 (13.0) 10 (13.7) |
134 (87.0) 63 (86.3) |
1 |
| Baseline NIHSS, median (IQR) | 15.5 (10.8-21.0) | 16.0 (11.0-20.0) | 0.803 |
| IV-FL, n (%) | |||
|
Yes No |
16 (11.0) 14 (17.3) |
130 (89.0) 67 (82.7) |
0.220 |
| Extracranial Lesion | |||
| 1. Etiology, n (%) | |||
|
Plaque Dissection |
20 (11.6) 10 (18.2) |
152 (88.4) 45 (81.8) |
0.252 |
| 2. Type, n (%) | |||
|
Occlusion Subocclusion or Stenosis |
23 (17.7) 7 (7.2) |
107 (82.3) 90 (92.8) |
0.028 |
| eCAS, n (%) | |||
|
Yes No |
6 (4.5) 24 (25.3) |
126 (95.5) 71 (74.7) |
<0.00001 |
| Antiplatelet Therapy | |||
| 1. All, n (%) | |||
|
Yes No |
10 (7.7) 20 (20.6) |
120 (92.3) 77 (79.4) |
0.006 |
| 2. Class, n (%) | |||
|
ASA P2Y12 Inhibitors GpIIb/IIIa Inhibitors |
6 (9.5) 0 (0) 4 (6.8) |
57 (90.5) 8 (100) 55 (93.2) |
0.810 |
|
1 Order of treatment, n (%) |
|||
|
Anterograde approach Retrograde approach |
4 (6.0) 2 (3.1) |
63 (94.0) 63 (96.9) |
1 |
| Timing-minutes, mean (SD) | |||
|
OTG GTR |
223.7 (89.4) 86.4 (36.1) |
257.7 (121.4) 74.9 (43.9) |
0.091 0.198 |
| Complications, n (%) | |||
|
Yes No |
2 (5.3) 28 (14.8) |
36 (94.7) 161 (85.2) |
0.186 |