Table 4.
Univariate analysis and multivariate predictors for SICH
Variable | No SICH (n = 205) |
Yes SICH (n = 22) |
p-value |
p-value (Wald’s test) |
OR (95% CI) |
---|---|---|---|---|---|
Age-years, mean (SD) | 65.7 (13.2) | 68.0 (10.6) | 0.366 | ||
Gender, n (%) | |||||
Male Female |
140 (90.9) 65 (89.0) |
14 (9.1) 8 (11.0) |
0.639 | ||
Baseline NIHSS, median (IQR) | 16.0 (11.0–20.0) | 18.0 (10.0–20.0) | 0.795 | ||
IV-FL, n (%) | |||||
Yes No |
130 (89.0) 75 (92.6) |
16 (11.0) 6 (7.4) |
0.486 | ||
Baseline ASPECTS, median (IQR) | 9.0 (8.0–10.0) | 8.0 (7.3–9.0) | 0.026 | < 0.0001 | 0.60 (0.51–0.70) |
Intracranial Lesion site, n (%) | |||||
ICA ICA T-type M1 M2 or distal Hemodynamic TLs |
13 (86.7) 37 (88.1) 83 (85.6) 40 (97.6) 32 (100) |
2 (13.3) 5 (11.9) 14 (14.4) 1 (2.4) 0 (0) |
0.035 | ||
Extracranial Lesion | |||||
1. Etiology, n (%) | |||||
Plaque Dissection |
153 (89.0) 52 (94.5) |
19 (11.0) 3 (5.5) |
0.299 | ||
2. Type, n (%) | |||||
Occlusion Subocclusion or Stenosis |
117 (90.0) 88 (90.7) |
13 (10.0) 9 (9.3) |
1 | ||
Collateral Flow, n (%) | |||||
Good Moderate Poor |
93 (93.9) 68 (90.7) 44 (83.0) |
6 (6.1) 7 (9.3) 9 (17.0) |
0.113 | ||
Anesthesia, n (%) | |||||
General Anesthesia Conscious Sedation |
94 (90.4) 111 (90.2) |
10 (9.6) 12 (9.8) |
1 | ||
Intracranial Thrombectomy, n (%) | |||||
TA SCoT |
98 (90.7) 57 (82.6) |
10 (9.3) 12 (17.4) |
0.160 | ||
eCAS, n (%) | |||||
Yes No |
112 (84.8) 93 (97.9) |
20 (15.2) 2 (2.1) |
0.001 | 0.002 | 8.18 (2.15-31.12) |
Antiplatelet Therapy | |||||
1. All, n (%) | |||||
Yes No |
113 (86.9) | 17 (13.1) | 0.067 | ||
2. Class, n (%) | |||||
ASA P2Y12 Inhibitors GpIIb/IIIa Inhibitors |
54 (85.7) 8 (100) 51 (86.4) |
9 (14.3) 0 (0) 8 (13.6) |
0.736 | ||
Order of treatment, n (%) | |||||
Anterograde approach Retrograde approach |
59 (88.1) 53 (81.5) |
8 (11.9) 12 (18.5) |
0.338 | ||
Timing-minutes, mean (SD) | |||||
OTG GTR |
250.3 (112.7) 74.4 (43.1) |
281.8 (160.3) 89.8 (43.8) |
0.379 0.131 |
||
Complications, n (%) | |||||
Yes No |
28 (73.7) 177 (93.7) |
10 (26.3) 12 (6.3) |
0.0008 | < 0.0001 | 6.27 (2.24–17.54) |
mTICI, n (%) | |||||
2b-3 0-2a |
158 (90.3) 47 (90.4) |
17 (9.7) 5 (9.6) |
1 | ||
Extracranial ICA Recanalization, n (%) | |||||
Yes No |
176 (89.3) 29 (96.7) |
21 (10.7) 1 (3.3) |
0.324 |