Table 6.

Standard error of measurement (SEM) and smallest detectable change (SDC) thresholds computed from year-1 and -2 follow-up MRIs of n = 21 knees from the test set

	corFLASH				sagDESS
	Manual		U-Net		Manual		U-Net
	SEM	SDC	SEM	SDC	SEM	SDC	SEM	SDC
Cartilage thickness (mm)
MFTC	0.09	0.24	0.07	0.21	0.07	0.20	0.10	0.28
LFTC	0.10	0.27	0.13	0.36	0.10	0.29	0.10	0.28
MT	0.05	0.14	0.04	0.11	0.05	0.13	0.05	0.15
cMF	0.06	0.16	0.05	0.15	0.06	0.16	0.08	0.21
LT	0.06	0.15	0.09	0.26	0.08	0.23	0.06	0.18
cLF	0.06	0.17	0.08	0.21	0.06	0.16	0.08	0.22
Cartilage volume (mm3)
MFTC	90	249	112	311	90	250	112	312
LFTC	98	273	153	424	118	326	175	484
MT	73	202	94	261	63	175	79	218
cMF	43	118	56	155	49	135	67	185
LT	83	231	113	314	100	277	120	332
cLF	43	119	79	219	41	113	89	247
Total area of subchondral bone (cm2)
MFTC	0.17	0.46	0.44	1.22	0.34	0.93	0.59	1.63
LFTC	0.18	0.49	0.64	1.77	0.25	0.68	0.63	1.75
MT	0.13	0.37	0.32	0.89	0.25	0.68	0.42	1.17
cMF	0.12	0.32	0.25	0.68	0.14	0.38	0.38	1.06
LT	0.15	0.41	0.53	1.47	0.18	0.49	0.39	1.08
cLF	0.10	0.29	0.33	0.93	0.16	0.45	0.36	0.99

SEM and SDC were computed from coronal FLASH (corFLASH) and sagittal DESS (sagDESS) MRI acquired at the OAI year-1 and -2 follow-up visits

MFTC/LFTC medial/lateral femorotibial compartment, MT/LT medial/lateral tibia, cMF/cLF central medial/lateral femoral condyle