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. 2021 May 26;11:11031. doi: 10.1038/s41598-021-90492-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Box plots for soluble fibrin, plasmin and antiplasmin complex (PAC), and plasminogen activator inhibitor-1 (PAI-1) at 0 and 3 h after presentation to the emergency department. Disseminated intravascular coagulation (DIC) patients showed significantly higher values of soluble fibrin and PAC at 0 and 3 h and PAI-1 at 3 h than did non-DIC patients. White box, non-DIC patients; grey box, DIC patients. Horizontal bars in the box indicate the median (middle) and interquartile ranges (upper 25% and lower 75%). Black boxes are mean values. *P < 0.05, **P < 0.01, ***P < 0.001 versus non-DIC patients.