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. 2021 May 26;11:11078. doi: 10.1038/s41598-021-90507-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Association of PARD3 with immune infiltration. (A) Association of PARD3 with immune infiltration (DCs dendritic cells, pDCs plasmacytoid DCs, iDCs immature DCs, aDCs activated DCs, Treg regulatory T cells, Tgd T gamma delta, Th helper T cells, Tfh T follicular helper, NK natural killer, Tem T effector memory, Tcm T central memory). (B–G) PARD3 was negatively related to infiltration of DCs, cytotoxic cells, pDCs, neutrophils, iDCs, and Treg (p < 0.01). (H–J) PARD3 was positively related to in infiltration of T helper cells, Th2 cells, and Tcm (p < 0.01).