Table 2.

Treatment-related toxicity by trial group

	Total no of participants (%)
	Overall		Group 1		Group 2		Group 3		Group 4
Toxicity	All	Gr 3	All	Gr 3	All	Gr 3	All	Gr 3	All	Gr 3
Overall	28 (100%)	3 (11%)	7	0	7	0	7	0	7	3
Injection site reaction	28 (100%)	0	7	0	7	0	7	0	7	0
Malaise/fatigue	18 (64%)	2 (7%)	2	0	6	0	5	0	5	2
Blood/bone marrow	16 (57%)	0	2	0	4	0	5	0	5	0
Rigors/chills	13 (46%)	0	1	0	4	0	4	0	4	0
Headache	10 (36%)	0	0	0	3	0	3	0	4	0
Back pain	1 (4%)	0	0	0	1	0	0	0	0	0
Joint pain	6 (21)	0	1	0	2	0	2	0	1	0
Muscle pain	8 (29%)	0	1	0	2	0	4	0	1	0
Pharynx/Larynx pain	3 (11%)	0	0	0	3	0	0	0	0	0
Rash	7 (25%)	1 (4%)	0	0	1	0	1	0	5	1
Anorexia/wt loss	10 (36%)	0	0	0	3	0	3	0	4	0
Pruritus	7 (25%)	0	1	0	1	0	1	0	4	0
Flu-like syndrome	5 (18%)	0	0	0	1	0	1	0	3	0
Cough	5 (18%)	0	0	0	2	0	1	0	3	0
Diarrhea	8 (29%)	0	2	0	2	0	2	0	2	0
Fever	7 (25%)	0	1	0	1	0	2	0	3	0
Nausea	7 (25%)	0	0	0	1	0	1	0	5	0
Flushing	7 (25%)	0	1	0	1	0	0	0	5	0
Sweating	7 (25%)	0	0	0	2	0	3	0	2	0

Gr, grade.