Table 3.
Baseline cohort demographics for patients with a prior psychiatric (F20–F48) diagnosis.
| CCB | Diuretic | CCB | ACEI | CCB | ARB | CCB | BB | |
|---|---|---|---|---|---|---|---|---|
| Number | 33,734 | 33,734 | 48,590 | 48,590 | 37,229 | 37,229 | 39,281 | 39,281 |
| Age at index (years) | 56.4 (15.0) | 56.5 (14.7) | 57.3 (14.8) | 57.1 (13.3) | 57.8 (14.1) | 58.0 (12.7) | 56.7 (14.2) | 57.1 (14.4) |
| Sex (M:F %) | 39: 61 | 38: 62 | 33: 67 | 33: 67 | 30: 70 | 31: 69 | 34: 66 | 34: 66 |
| Race (% W, B, O)b | 77, 17, 6 | 76, 17, 7 | 79, 16, 5 | 79, 15, 6 | 84, 10, 6 | 83, 10, 7 | 75, 19, 6 | 75, 19, 6 |
| Blood pressure | 134/79 | 132/78 | 134/78 | 134/79 | 133/77 | 132/78 | 136/80a | 130/76b |
| Prior diuretic (%) | – | – | 41 | 42 | 44 | 51 | 41 | 36 |
| Prior ACEI (%) | 30 | 34 | – | – | 44 | 35 | 36 | 28 |
| Prior ARB (%) | 12 | 15 | 28 | 4 | – | – | 18 | 11 |
| Prior BB (%) | 35 | 33 | 40 | 31 | 44 | 35 | – | – |
| Prior other AHT (%) | 14 | 10 | 16 | 10 | 16 | 10 | 12 | 10 |
| Prior F20–29 (%) | 6 | 5 | 6 | 6 | 6 | 3 | 6 | 7 |
| Prior F30–39 (%) | 65 | 67 | 66 | 67 | 68 | 66 | 67 | 66 |
| Prior F40–48 (%) | 64 | 62 | 64 | 61 | 63 | 63 | 62 | 64 |
| Prior F10–19 (%) | 25 | 24 | 24 | 25 | 28 | 19 | 25 | 24 |
| Prior antidepressant (%) | 59 | 57 | 60 | 59 | 63 | 64 | 60 | 58 |
| Prior anxiolytic (%) | 53 | 49 | 55 | 48 | 57 | 52 | 49 | 53 |
| Prior antipsychotic (%) | 12 | 10 | 12 | 10 | 12 | 7 | 10 | 12 |
Cohorts propensity score-matched for age, sex, race, and blood pressure (most recent recorded value). “Prior” means any occurrence before the start of the exposure period.
aBlood pressure could not be matched for CCB vs BB (SD = 0.31 for systolic and diastolic).
bW: white. B: black or African American. O: other or not known.