Table 2.
Multivariable logistic regression model for predicting pediatric urinary tract infections caused by gram-positive bacteria.
| Variable | Crude OR | Model 1 | Model 2 | Model 3 |
|---|---|---|---|---|
| (95% CI) | (95% CI) | (95% CI) | (95% CI) | |
| N | N = 3783 | N = 3783 | N = 2632 | N = 2529 |
| Age at UA order ≥ 24 months | 5.90 (4.19, 8.31) | 3.98 (2.25, 7.03) | 3.01 (1.37, 6.63) | 3.21 (1.31, 7.89) |
| Boy | 0.54 (0.40, 0.75) | 1.04 (0.73, 1.47) | 1.71 (1.03, 2.82) | 1.69 (0.97, 2.94) |
| Sample obtained from catheter, PCN, or suprapubic | 4.54 (3.24, 6.36) | 1.29 (0.75, 2.23) | 1.21 (0.57, 2.55) | 1.22 (0.52, 2.84) |
| No prior antibiotic use | 2.43 (1.39, 4.24) | 2.21 (1.24, 3.93) | 3.20 (1.25, 8.21) | 3.13 (1.12, 8.75) |
| No prior Foley catheterization | 4.15 (2.61, 6.59) | 1.70 (1.00, 2.89) | 1.80 (0.94, 3.43) | 1.44 (0.74, 2.83) |
| Serum biochemical profiles | ||||
| WBC < 14.4 × 103/μL | 3.96 (2.46, 6.38) | – | 2.90 (1.70, 4.93) | 2.19 (1.25, 3.83) |
| hsCRP < 3.4 mg/dL | 3.33 (2.03, 5.48) | – | 2.09 (1.23, 3.52) | 2.18 (1.24, 3.85) |
| Hemoglobin ≥ 11.3 g/dL | 4.54 (2.74, 7.50) | – | 2.16 (1.19, 3.90) | 1.90 (1.03, 3.51) |
| Urinalysis | ||||
| Bacteria+ | 0.35 (0.25, 0.50) | – | – | 1.08 (0.63, 1.85) |
| Leukocyte esterase− | 5.11 (3.58, 7.29) | – | – | 3.19 (1.88, 5.42) |
| Nitrite− | 8.15 (4.51, 14.73) | – | – | 4.13 (1.87, 9.14) |
| WBC < 420/μL | 3.45 (2.39, 4.96) | – | – | 2.37 (1.18, 4.79) |
| RBC < 22/μL | 1.38 (1.01, 1.88) | – | – | 1.42 (0.82, 2.44) |
| C-statistic | 0.745 (0.688, 0.801) | 0.806 (0.753, 0.860) | 0.879 (0.845, 0.913) | |
CI confidence interval, hsCRP high sensitivity C-reactive protein, OR odds ratio, PCN percutaneous nephrostomy, RBC red blood cell, UA urinalysis, WBC white blood cell.