Fig. 2. SEC61G expression is upregulated in breast cancer tissues and cell lines.
A Representative SEC16G immunohistochemical (IHC) with different scores based on staining intensity in breast cancer tissue microarray. B Representative SEC61G IHC staining in breast cancer tissues and adjacent non-tumor normal tissues. C Comparison of IHC staining score distributions between breast cancer tissues and adjacent non-tumor normal tissues. D The protein expression of SEC61G in 16-paired breast cancer tissues (T) and adjacent normal tissues (N) was assessed by western blot. E, F The protein and mRNA expression of SEC61G in normal breast epithelial cell MCF-10A and breast cancer cell lines (SK-BR-3, T47D, MCF-7, BR-549, and MDA-MB-231) was analyzed by western blot or qRT-PCR. *P < 0.05, **P < 0.01.
