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. 2021 May 26;11:11004. doi: 10.1038/s41598-021-90092-y

Figure 3.

Figure 3

In-vivo follow up of elastin with the aid of cardiac MRI in wild-type mice 30 days after permanent ligation (A). The arrows represent ESMA uptake in exemplary images. Cardiac MRI image of CCR2-KO mice 30 days after permanent ligation (B). Cardiac MRI 30 days after permanent ligation in CX3CR1-KO mice (C). Cardiac MRI 30 days after permanent ligation in MCP-1-KO mice (D), (E) shows increased expansion index in CCR2-Ko mice compared to MCP-1-KO mice 30 days after MI as sign for increased myocardial scar with decreased ability of contraction. In (F) SNR was increased in CCR2-KO mice compared to MCP1-KO-mice 30 days after MI, although statistically not relevant also as a sign for extended myocardial scar.