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. 2021 May 26;11:10967. doi: 10.1038/s41598-021-90435-9

Table 2.

Clinical features of ischemic stroke patients stratified according to telomere length.

Telomere length p
≤ 5.5 kb (n = 59) > 5.5 kb (n = 104)
Age 77 (67–84) 67 (52–74) < 0.001
Female gender 35 (59%) 45 (43%) 0.049
Hypertension 50 (85%) 73 (70%) 0.038
Diabetes Mellitus 26 (44%) 34 (33%) 0.148
Coronary artery disease 26 (44%) 27 (26%) 0.018
Hyperlipidemia 32 (54%) 61 (59%) 0.584
Active smoking 10 (17%) 25 (24%) 0.289
Admission NIHSS score 6 (3–17) 4 (2–9) 0.039
Admission DWI lesion volume (mL) 6.0 (1.1–30.7) 6.4 (0.9–28.1) 0.585
CCS stroke subtype 0.221
   Large artery atherosclerosis 11 (19%) 18 (17%)
   Cardio-aortic embolism 23 (39%) 30 (29%)
   Small artery occlusion 5 (9%) 6 (6%)
   Other causes 0 (0%) 6 (6%)
   Undetermined 20 (34%) 44 (42%)
90-day mRS ≤ 2 26 (44%) 66 (63%) 0.016
Death 12 (20%) 8 (8%) 0.018