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. 2021 May 26;11:11001. doi: 10.1038/s41598-021-90215-5

Table 2.

Demographics of patients with nCRT.

Before propensity score matching After propensity score matching
Open
(n = 71)
MIS
(n = 42)
p Open
(n = 42)
MIS
(n = 42)
p
Age (years, median ± (SD) 57 ± 12 55 ± 10 0.341 58 ± 12 55 ± 10 0.158
Sex, n (%) 0.846 0.503
Male 42 (59.2) 24 (57.1) 27 (64.3) 24 (57.1)
Female 29 (40.8) 18 (42.9) 15 (35.7) 18 (42.9)
BMI (kg/m2) 23.1 ± 3.6 23.3 ± 4.7 0.839 22.7 ± 2.6 23.3 ± 4.7 0.123
ASA score, n (%) 1.000 1.000
 < 3 70 (98.6) 42 (100.0) 41 (97.6) 42 (100.0)
 ≥ 3 1 (1.4) 0 (0.0) 1 (2.4) 0 (0.0)
Underlying, n (%) 33 (46.5) 17 (40.5) 0.562 24 (57.1) 17 (40.5) 0.127
HTN 23 (32.4) 12 (28.6) 0.682 16 (38.1) 12 (28.6) 0.355
DM 7 (9.9) 9 (21.4) 0.101 4 (9.5) 9 (21.4) 0.131
IHD 3 (4.2) 1 (2.4) 1.000 2 (4.8) 1 (2.4) 0.500
COPD 8 (11.3) 0 (0.0) 0.025 7 (16.7) 0 (0.0) 0.012
Preoperative CEA (ng/mL) 2.1 ± 2.7 2.7 ± 2.7 0.268 2.5 ± 3.0 2.7 ± 2.7 0.778
Preoperative CA19-9 (ng/mL) 14.3 ± 21.6 13.3 ± 12.0 0.241 11.6 ± 6.0 13.3 ± 12.0 0.367
Tumor distance from AV (cm) 3.0 ± 1.3 2.9 ± 1.7 0.485 2.6 ± 1.1 2.9 ± 1.7 0.425
Adjuvant treatment, n (%) 59 (83.1) 33 (78.6) 0.620 35 (83.3) 33 (78.6) 0.578

nCRT neoadjuvant chemoradiotherapy, MIS minimally invasive surgery, BMI body mass index, ASA American society of anesthesiologists, HTN hypertension, DM diabetes mellitus, IHD ischemic heart disease, COPD chronic obstructive pulmonary disease, CEA carcinoembryonic antigen, AV anal verge.