Table 4.
Pathologic characteristics of patients treated with and without nCRT.
| Before propensity score matching | After propensity score matching | |||||
|---|---|---|---|---|---|---|
| Open (n = 147) |
MIS (n = 166) |
P | Open (n = 118) |
MIS (n = 118) |
p | |
| Size of primary tumor (cm) | 3.0 ± 1.6 | 2.7 ± 1.6 | 0.051 | 3.0 ± 1.6 | 2.7 ± 1.5 | 0.193 |
| Proximal resection margin (cm) | 14.1 ± 6.2 | 13.9 ± 5.3 | 0.841 | 14.2 ± 6.5 | 13.7 ± 4.9 | 0.557 |
| Distal resection margin (cm) | 1.3 ± 1.8 | 1.4 ± 1.5 | 0.756 | 1.6 ± 3.7 | 1.5 ± 2.4 | 0.950 |
| CRM (mm) | 5.7 ± 3.9 | 6.3 ± 3.9 | 0.355 | 6.1 ± 4.0 | 6.4 ± 3.7 | 0.653 |
| CRM positive, n (%) | 9 (6.1) | 8 (4.8) | 0.612 | 8 (6.8) | 6 (5.1) | 0.582 |
| Tumor grade, n (%) | 0.116 | 0.120 | ||||
| Well differentiated | 23 (15.6) | 45 (27.1) | 18 (15.3) | 33 (28.0) | ||
| Moderately | 110 (74.8) | 110 (66.3) | 91 (77.1) | 77 (65.3) | ||
| Poorly differentiated | 6 (4.2) | 7 (4.2) | 4 (3.4) | 6 (5.1) | ||
| Mucinous carcinoma | 4 (2.7) | 2 (1.2) | 3 (2.5) | 1 (0.8) | ||
| Signet ring cell | 4 (2.7) | 2 (1.2) | 2 (1.7) | 1 (0.8) | ||
| Lymphatic invasion, n (%) | 28 (19.0) | 35 (20.6) | 0.731 | 23 (19.5) | 28 (23.7) | 0.429 |
| Vascular invasion, n (%) | 15 (10.2) | 14 (7.9) | 0.473 | 9 (7.6) | 11 (9.3) | 0.640 |
| Perineural invasion, n (%) | 4 (2.7) | 17 (9.7) | 0.012 | 2 (1.7) | 15 (12.7) | 0.002 |
| TNM stage, n (%) | 0.032 | 1.000 | ||||
| 0 | 20 (13.6) | 16 (9.6) | 11 (9.3) | 11(9.3) | ||
| I | 49 (33.3) | 80 (48.2) | 48 (40.7) | 48 (40.7) | ||
| II | 37 (25.2) | 26 (15.7) | 26 (22.0) | 26 (22.0) | ||
| III | 41 (27.9) | 44 (26.5) | 33 (28.0) | 33 (28.0) | ||
| Pathologic T stage, n (%) | 0.044 | 0.869 | ||||
| T0 | 21 (14.2) | 18 (10.8) | 12 (10.2) | 12 (10.2) | ||
| T1 | 16 (10.9) | 27 (16.3) | 15 (12.7) | 20 (16.9) | ||
| T2 | 43 (29.3) | 68 (41.0) | 42 (35.6) | 39 (33.1) | ||
| T3 | 66 (44.9) | 51 (30.7) | 48 (40.7) | 45 (38.1) | ||
| T4 | 1 (0.7) | 2 (1.2) | 1 (0.8) | 2 (1.7) | ||
| Pathologic N stage, n (%) | 0.477 | 0.964 | ||||
| N0 | 106 (72.1) | 122 (73.5) | 85 (72.0) | 85 (72.0) | ||
| N1 | 28 (19.0) | 35 (21.1) | 23 (19.5) | 24(20.3) | ||
| N2 | 13 (8.9) | 9 (5.4) | 10 (8.5) | 9 (7.7) | ||
| Harvested lymph nodes (n) | 15.3 ± 7.7 | 13.8 ± 5.6 | 0.059 | 13.4 ± 7.6 | 12.6 ± 4.4 | 0.313 |
nCRT neoadjuvant chemoradiotherapy, MIS minimally invasive surgery, CRM circumferential resection margin.