Table 1.
Demographics of the acute ischemic stroke patients and comparison of clinical and brain image findings according to clinical outcome at three months after index stroke.
| Total | mRS < 3 (n = 159) |
mRS ≥ 3 (n = 39) |
p value | |
|---|---|---|---|---|
| Demographics | ||||
| Sex, male | 116 (58.5) | 98 (61.6) | 18 (46.1) | 0.102 |
| Age, years | 63.7 ± 12.5 | 62.8 ± 11.8 | 67.5 ± 14.6 | 0.034 |
| Body mass index, kg/m2 | 24.0 ± 3.5 | 24.1 ± 3.4 | 23.5 ± 3.9 | 0.345 |
| Risk factors | ||||
| Hypertension | 115 (58.0) | 91 (57.2) | 24 (61.5) | 0.718 |
| Diabetes mellitus | 85 (42.9) | 66 (41.5) | 19 (48.7) | 0.472 |
| Hypercholesterolemia | 56 (28.2) | 46 (28.9) | 10 (25.6) | 0.843 |
| Coronary artery disease | 41 (20.7) | 29 (18.2) | 12 (30.8) | 0.120 |
| Smoking | 76 (38.3) | 58 (36.5) | 18 (46.2) | 0.276 |
| Alcohol intake | 58 (29.2) | 43 (27.0) | 15 (38.5) | 0.173 |
| Prior medication | ||||
| Antithrombotics | 44 (22.2) | 35 (22.0) | 9 (23.1) | 1.000 |
| Statins | 46 (23.2) | 41 (25.8) | 5 (12.8) | 0.094 |
| NIHSS | 4 [2–6] | 3 [1–3] | 10 [7–16] | 0.001 |
| Cerebral atherosclerosis | 88 (44.4) | 63 (39.6) | 25 (64.1) | 0.006 |
| High-grade white matter hyperintensities | 41 (20.7) | 31 (19.5) | 10 (25.6) | 0.396 |
| Stroke subtype | 0.055 | |||
| Cardioembolism | 31 (15.6) | 22 (13.8) | 9 (23.1) | |
| Large artery atherosclerosis | 78 (39.4) | 59 (37.1) | 19 (48.7) | |
| Small vessel occlusion | 99 (50.0) | 78 (49.1) | 11 (28.2) | |
| Blood laboratory findings | ||||
| Fasting glucose, mg/dL | 117.0 ± 44.3 | 116.2 ± 44.5 | 120.2 ± 43.5 | 0.612 |
| HbA1c, % | 6.6 ± 1.5 | 6.5 ± 1.5 | 6.9 ± 1.6 | 0.243 |
| Triglyceride, mg/dL | 122.8 ± 100.1 | 126.1 ± 107.7 | 109.1 ± 59.0 | 0.343 |
| Total cholesterol, mg/dL | 177.1 ± 38.5 | 175.5 ± 38.5 | 183.4 ± 38.2 | 0.253 |
| Low density lipoprotein, mg/dL | 115.9 ± 36.7 | 114.7 ± 36.2 | 120.9 ± 38.9 | 0.345 |
| White blood cell count, × 103 | 7.4 ± 2.5 | 7.0 ± 2.3 | 8.8 ± 2.9 | 0.001 |
| Hemoglobin, mg/dL | 13.4 ± 1.8 | 13.5 ± 1.8 | 13.2 ± 1.7 | 0.327 |
| Creatinine, mg/dL | 1.0 ± 0.9 | 0.9 ± 0.6 | 1.2 ± 1.4 | 0.222 |
| Albumin, mg/dL | 3.7 ± 0.3 | 3.7 ± 0.3 | 3.6 ± 0.4 | 0.082 |
| Uric acid, mg/dL | 4.8 ± 1.6 | 4.8 ± 1.3 | 5.1 ± 2.4 | 0.422 |
| C-reactive protein, mg/L | 0.7 ± 1.7 | 0.6 ± 1.4 | 2.2 ± 5.1 | 0.018 |
Data are shown as n (%), mean ± standard deviation, or median [interquartile range].
mRS modified Rankin scale, NIHSS National Institutes of Health Stroke Scale.