Table 3.

Example questions to ask patients to facilitate reporting of new corneal-related AEs with belamaf treatment.

During conversations with patients regarding the effects of their treatment, it may be helpful to ask the following questions regarding new corneal AEs they may be experiencing with belamaf:

• Are you finding it difficult to read during the day due to your eyesight? Or at night?

• Have you noticed any problems with your eyesight while driving?

• Do you have any problems with your eyes or vision when using a computer/tablet/phone or watching the television?

◦ Have you needed to increase the font size on your devices so that you can see the text better?

• Have you noticed any vision changes or other symptoms when you engage in any other activities that are important to you?

• Have you experienced any pain or discomfort in or around your eyes?

• Are your eyes more sensitive than usual to light?

◦ Have you needed to turn off the lights or wear sunglasses indoors because you were more sensitive to light?

• Have you noticed any other symptoms related to your eyes or eyesight?

◦ Foreign body sensation?

◦ Watering eyes?

◦ Other (patient to indicate)?

AE adverse event.