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. 2021 Mar 13;17(2):285–301. doi: 10.1007/s11302-021-09779-6

Table 1.

Behavioral parameters in the OFT of mice administered with guanosine (0.05 mg/kg, p.o.) 1 h, 6 h, and 24 h before the session

Vehicle Guanosine (1 h) t values
Latency to exit the first quadrant(s) 12.14 ± 1.10 15.50 ± 2.25 t(13) = -1.28, p = 0.22
Numbers of rearings 6.86 ± 2.89 5.87 ± 1.84 t(13) = 0.29, p = 0.77
Total time of grooming (s) 40.85 ± 6.35 38.37 ± 10.77 t(13) = 0.19, p = 0.85
Total time in center of the OFT (s) 2.14 ± 0.91 3.38 ± 1.76 t(13) = -0.59, p = 0.56
N° of entries in center of the OFT 2.29 ± 0.99 2.75 ± 1.26 t(13) = -0.28, p = 0.78
Vehicle Guanosine (6 h) t values
Latency to exit the first quadrant   16.63 ± 3.20   15.28 ± 1.44   t(13) = 0.36, p = 0.72
Numbers of rearings   5.75 ± 2.25   11.42 ± 3.66   t(13) = -1.36, p = 0.20
Total time of grooming   62.37 ± 11.10   68.57 ± 12.95   t(13) = -0.36, p = 0.72
Total time in center of the OFT   1.13 ± 0.48   1.29 ± 0.75   t(13) = -0.19, p = 0.86
N° of entries in center of the OFT   1.23 ± 0.48   1.28 ± 0.75   t(13) = -0.19, p = 0.86
Vehicle Guanosine (24 h) t values
Latency to exit the first quadrant   23.13 ± 9.87   12.87 ± 1.11   t(14) = 1.03, p = 0.32
Numbers of rearings   10.00 ± 1.25   8.63 ± 1.08   t(14) = 0.83, p = 0.42
Total time of grooming   31.75 ± 7.67   40.63 ± 3.74   t(14) = -1.04, p = 0.32
Total time in center of the OFT   1.75 ± 0.75   0.38 ± 0.26   t(14) = 1.73, p = 0.11
N° of entries in center of the OFT   1.75 ± 0.75   0.50 ± 0.27   t(14) = 1.57, p = 0.14