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. 2021 May 26;11:11056. doi: 10.1038/s41598-021-90755-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differently expressed RNAs in TCGA lung adenocarcinoma. (A) The heatmap of the miRNAs expression in LUAD, and the volcano graph shows the distribution of differently expressed miRNAs. (B) The heatmap of the lncRNAs expression in LUAD, and the volcano graph shows the distribution of differently expressed lncRNAs. (C) The heatmap of the mRNAs expression in LUAD, and the volcano graph shows the distribution of differently expressed mRNAs. In the volcano graph, the X axis represents the fold changes of DEGs, and the Y axis represents the adjusted p-value, red dots present up-regulated genes and blue dots present down-regulated genes (log fold change > 1.0, p-value < 0.05).