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. 2021 Jan 15;15(3):309–318. doi: 10.4162/nrp.2021.15.3.309

Table 2. Follow-up values for the caffeine intake and sleep status variables according to the three intervention groups.

Variables Intervention groups*
Group A Group B Group C
Placebo γ-PGA Placebo VitB6 Placebo γ-PGA + VitB6
Caffeine intake (mg/day) 315.9 ± 340.4 237.5 ± 212.8 143.2 ± 147.1 82.1 ± 105.3 232.7 ± 165.2 290.6 ± 184.0
Sleep duration (hours/day) 6.75 ± 1.26 7.01 ± 1.36 7.12 ± 1.65 7.66 ± 1.22 6.51 ± 1.35 7.09 ± 1.16
PSQI 4.68 ± 2.38 5.18 ± 2.56 4.92 ± 1.68 5.00 ± 1.88 5.47 ± 3.46 4.17 ± 3.22
ESS 5.62 ± 3.93 5.31 ± 3.40 5.50 ± 2.76 5.14 ± 3.10 6.52 ± 3.79 6.47 ± 3.67
Serum serotonin (ng/mL) 175.1 ± 43.1 192.1 ± 54.5 125.8 ± 59.2 134.4 ± 47.5 183.6 ± 40.3 168.8 ± 28.3

Variable values are presented as mean ± SD.

γ-PGA, poly-γ-glutamic acid; VitB6, vitamin B6; PSQI, Pittsburgh Sleep Quality Index; ESS, Epworth Sleepiness Scale.

*Group A received γ-PGA supplementation only; Group B received VitB6 supplementation only; Group C received both γ-PGA and VitB6 supplementation.