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. 2021 Jan 15;15(3):309–318. doi: 10.4162/nrp.2021.15.3.309

Table 3. Differences in the baseline and follow-up values according to the three intervention groups.

Variables Intervention groups*
Group A Group B Group C
Placebo γ-PGA Placebo VitB6 Placebo γ-PGA + VitB6
Caffeine intake (mg/day) 32.6 ± 170.5 −14.0 ± 317.8 −14.9 ± 128.8 −66.2 ± 119.8 −1.84 ± 98.5 −8.16 ± 63.1
Sleep duration (hours/day) 0.03 ± 1.04 −0.03 ± 0.71 0.14 ± 0.86 0.67 ± 0.80 −0.25 ± 1.25 0.27 ± 0.98
PSQI −0.06 ± 1.73 0.31 ± 1.53 −0.92 ± 1.30 −0.50 ± 1.95 0.64 ± 1.93 −0.52 ± 1.58
ESS −0.18 ± 2.83 −0.68 ± 2.33 −0.14 ± 2.38 −1.21 ± 3.04 0.11 ± 1.72 −0.11 ± 1.49
Serum serotonin (ng/mL) −2.50 ± 50.8 1.93 ± 47.7 11.5 ± 54.0 −4.25 ± 49.5 17.9 ± 60.5 4.59 ± 38.5

Variable values are presented as mean ± SD.

γ-PGA, poly-γ-glutamic acid; VitB6, vitamin B6; PSQI, Pittsburgh Sleep Quality Index; ESS, Epworth Sleepiness Scale.

*Group A received (γ-PGA supplementation only; Group B received VitB6 supplementation only; Group C received both γ-PGA and VitB6 supplementation. P<0.05 when being compared with a placebo group in each intervention. Comparison was performed using a nonparametric test.