Table 2. Impact of Back Pocket Substituents on Potency.
Each kinact and KI value was obtained from an average of two independent determinations (±SD). The method is described in the Supporting Information.
CD69 expression on mouse splenocytes was measured after stimulation with anti-IgM. nd = not determined.
Inhibition of anti-IgD-induced activation of B cells (B220+CD86+).
n = 1.